Ophthalmic Vigilance in Antiangiogenic Pharmacotherapy
نویسنده
چکیده
Background: Vascular endothelial growth factor (VEGF) plays an important role in the pathophysiology of several sight-threatening retinal disorders such as age-related macular degeneration, retinal vein occlusion, diabetic macular edema and proliferative diabetic retinopathy. The discovery of anti-VEGF agents has revolutionized the treatment of these conditions. Ophthalmology has witnessed an explosion in the number of intravitreal injections delivered to patients over the past 10 years, driven in large part by the introduction and rapid incorporation of therapy with anti-VEGF agents. Currently several anti-angiogenicagents are being widely and successfully used for the treatment of eye diseases. However, there is some evidence that intravitreal Antiangiogenic injections may result in injection-related ocular side effects. This mandates awareness on the matter.
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